Abstract
An investigation has been carried out to evaluate the in vitro hepatoprotective effect of extract of Commiphora caudate(wight&arn)Engl using antitubercular drugs(Isoniazid, Pyrazinamide, Rifampicin) and D (+)-Galactosamine as toxicant and silymarin as standard drug by MTT assay[(3-(4,5 dimethylthiazole –2 yl)-2,5 diphenyl tetrazolium bromide) assay. Commiphora Caudata (Burseraceae) is a potential medicinal plant used traditionally in the treatment of rheumatism, ulcers, diarrhea and diabetes. The present investigation was aimed to study the effect of ethanolic extract of Commiphora Caudata for evaluation of the hepatoprotective activity of on the BRL3A (Rat, Liver cell line) cell line. The various solvent extracts were tested for its inhibitory effect on BRL3A (Rat, Liver cell line) cell line. The percentage viability of the cell line was carried out. However, a very limited information available on the pharmacological activity of this plant . Hence, it was proposed to carry out a preliminary in vitro analysis of the hepato protective activity of the plant, which gave promising results. The results of this study indicate that roots extracts of plants have good potentials for use in hepatic disease.
