Abstract
Thiadiazoles having a wide range of activity so based on this concept we have focused on 1,3,4 Thiadiazoles which are having a free amino group so that Schiff bases can be prepared by using corresponding substituted benzaldehydes. The progress of reaction was monitored by TLC, then the synthesized compounds were crystallized by using suitable solvents. Then all of them were characterized by I.R and 3 of them by N.M.R spectra. Finally the compounds were tested for in-vitro anti cancer activity on colorectal cell lines (HT-29).
