Abstract
Lozenges are tablets that dissolve slowly in the mouth and so release the drug in the saliva. Lozenges are used for the local medication dissolving in the mouth or throat, e.g. it will produce local anaesthesia, antiseptic and antibiotic action of drugs. There are different types of lozenges such as Chewable Lozenges, Hard Lozenges, and Soft Lozenges. Chewable lozenges are popular with the paediatric population. Hard-candy lozenges are mixtures of sucrose and other sugars and/or carbohydrates in an amorphous state. Soft lozenges have become popular because of the ease of extemporaneous preparation and applicability to a wide variety of drugs. The lozenges are prepared by direct compression and Wet granulation method. Ordered mixing, Drug adsorption, Drug excipient hybrid mixing by spray drying these are methods by which compressed tablet lozenges are prepared. There are some evaluation parameters by which lozenges will be evaluated such as diameter, weight variation, friability, hardness, In-vitro drug dissolution studies, Stability studies etc.
