Abstract
Now a days majority of drug manufactured by synthetic process, so large volume of drug produce which are highly water in soluble drugs but having no issue on permeability, means BCS class II category drugs. To improve the status of such major problem many approaches have been introduced for the solubility enhancement of such drugs. SD is usually one of the most widely and adopted technology used for this purpose.. Poor water solubility is the major drawback for the various types of drugs and various approaches have been introduced so far for the solubility enhancement of such drugs. Solid dispersion is one of unique technique adopted for the formulation of such drugs and various novel methods were used for the preparation of solid dispersion. Solid dispersion techniques have attracted majority because of low cost & due to improving the dissolution rate of highly lipophilic drugs and hence their bioavailability. This article reviews on classification, various preparation methods, advantages and disadvantages of solid dispersion.
