Abstract
Nature has given support for mankind in all means. In the Pharmaceutical novel drug delivery dosage form it plays a important role for developing newer novel and stable dosage form. In this the mucoadhesive buccal delivery is one of the promising field in which so many drugs are designed for the health of nations. In this buccal delivery system to attain good therapeutic and stable polymers is necessary. From the available literatures so many products are formulated with synthetic and semi synthetic polymers .The aim of this article is explain the isolation of polymer from Diospyros pergrina and Dillenia indica which abundantly present in the earth and compare the evaluation parameters with available mucoadhesive polymers. The isolation of natural polymer from Indian Persimmon Fruits and Elephant apple fruit and performed the evaluation parameters for suitability for mucoadhesion and comparing with HPMC, sodium alginate, guar gum.Sodium carboxy methyl cellulose. From the datas the natural mucoadhesive polymers has more compatible and more suitable polymer alone and or with other combinations of polymers for developing optimized formulas and also very much suitable for developing novel drug delivery by buccal delivery especially for low bioavailable drugs.
