Abstract
Isatin are known for their various biological activities. By suitable control of a substituent different novel Indole 2,3-diones were synthesized. In this present study various Schiff and Mannich bases were synthesized, characterized and evaluated for their antimicrobial activity. The compounds were prepared by reacting indole 2,3-dione with 4-substituted benzyl chloride to give intermediate, and also Isatin reacted with morpholine to give mannich base which was then it is fused with 3-amino-2phenylquionazolin4 (H)-one,to give final product. All the synthesized compounds were characterized by various methods like TLC, MP, FTIR, 1HNMR and Mass spectroscopy. The compounds have been evaluated for their antimicrobial activity.
