The achievement and maintenance of optimal glycemic control are critical steps among diabetics to prevent complication. The discovery of insulin has been a cornerstone for diabetes care. The continued prevalence of the disorder and the changing prescribing patterns with the fluctuating blood sugar level indicate to evaluate the clinical management of this disorder. Hence this Cross-sectional observational study was carried out in the Department of General Medicine, Sri Ramachandra University, India for a period of 6 months. The demographic and treatment details of patients were collected in a structured data collection form and analyzed. Data of 350 patients were collected and analyzed, of which 47.4 % were male and 52.2% were female. The mean age was 58.6 ±9.26 years. Insulin as monotherapy was observed for 39.71% patients and 60.28% patients were prescribed with combination therapy. The most commonly prescribed insulin was Human Mixtard 30/70 and combination of Insulin ® with Insulin (Neutral) which had a better glycemic control among our study population. The preferred oral hypoglycemic agent was metformin which was well tolerated in patients who were willing to continue with oral therapy. From the study findings it can be concluded that the prescribing trend of insulin was away from monotherapy and individualized according to patients need.
