Abstract
The present research work discusses the development of UV spectrophotometry method for estimation of Fluvoxamine maleate. The simple, accurate and novel method has been developed for estimation of Fluvoxamine maleate in bulk and pharmaceutical dosage form. The optimum conditions for the analysis of drug were established. Beer’s law is obeyed in the range of 5-10 µg/ml at λmax of 246 nm using 0.1N Hydrochloric acid as solvent. Calibration curve shows a linear relationship between the absorbance and concentration. The line equation Y = 0.026x + 0.0803 with r2 of 0.9999 was obtained. The developed method was validated according to ICH guidelines and was found to be accurate and precise. The proposed method can be successfully applied for the estimation of Fluvoxamine maleate in bulk and pharmaceutical dosage forms. Results of the analysis were validated statistically and by recovery studies.
