In present investigation formulation of Efavirenz dispersion using Polymer like PEG 6000 and HPMC can be used to prepare inclusion complexes of Efavirenz with improved solubility of the drug. Phase solubility studied of drug with PEG 6000 illustrates the solubility enhancement. The phase solubility of pure drug, physical mixture and solid dispersion was found to be 66.12 and 57.21?g/nm. respectively. FT-IR studied indicated the formation of true complex of Efavirenz and PEG6000 in 1:2 molar ratio prepared by solvent evaporation method. The dissolution of Efavirenz from inclusion complex prepared by fusion, solvent evaporation method was found to be higher than the pure drug and other prepared complexes. Enhancement of the solubility of Efavirenz PEG600 solvent evaporation complex was 96.76% in 90 min with 3 fold in its dissolution rate.