Alzheimer's disease (AD) is a progressive brain disease that affects a person's memory, learning ability, intellectual, judgment, communication, and daily activities over time. Clinically, Alzheimer's disease is marked by cognitive impairment, while pathologically, it is marked by the formation of amyloid plaques and neurofibrillary tangles, as well as the degradation of the cholinergic basal forebrain. The primary neurotransmitter defect discovered in AD involved acetylcholine as cholinergic function is vital for temporary memory. Although the Food and Drug Administration has official numerous medicines for the handling of Alzheimer's disease, the results have not been satisfactory, and alternative medicine, including herbal therapy, has a role. Herbal remedies for Alzheimerâs disease have become more and more popular in the recent years, some herbs that is Saga, Gotu Kala, Jyotishmati, Brahmi, Shankhpusph, Lavender, Chinese date and Saffron are useful for cognitive impairment of Alzheimer's disease. Most of the plants have been chemically evaluated with their proven efficacy in clinical trials. Current review summarizes data concerning the sources, chemistry, biological actions and clinical applications of these plants to give adequate baseline facts that could be used in drug discovery &development process, thereby providing new functional molecules for Alzheimer's disease.
