Standardization of a Siddha herbo-mineral formulation is essential in order to assess the quality of drugs based on the concentration of their active principles, physical, chemical, phytochemical, in-vitro, in-vivo parameters. All the plant and mineral materials were identified and authenticated by the Botanist and Gunapadam (Siddha Pharmacology) experts in Government Siddha Medical College, Arumbakkam, Chennai - 106. FTIR is used to identify the functional group, to determine the quality and consistency of the sample. SEM gives the information about the sample and it includes external morphology, texture, its crystalline structure, chemical composition and it displays the shape of the sample. ICPOES helps to analyze the major and minor elements in solution sample. FTIR shows the presence of alcohol, alkanes, alkenes, alkynes, amide, amine, aromatic, ester, ether and nitro groups. SEM results reveal the presence of micro particles ranging from 238nm, 280nm, 306nm. ICPOES shows the presence of Ca, Fe, K, Na, P and S has physiologically important. In Sandhanathy Chooranam, the heavy metals like As, Cd, Hg, Pb and Ni were below detectable level. This reveals the safety of the drug. Based on the results Sandhanathy Chooranam is a safe drug.
