Formulation development is the most emerging and upcoming face of pharmaceutical technology in the current era. The day-to-day advancements in the research have provided an edge to this brilliant branch of pharmaceutical sector for not only uplifting the pharmacy profession but also to conquer the diseased state for nurturing the health and humanity. The fluid-bed technology or air-suspension process is the potential tool to develop newer trends and implications in the sector of formulation development with maximum therapeutic efficacy. Fluid bed granulation is a key pharmaceutical process which improves many of the powder properties for tablet compression. Granules of high quality can be obtained by understanding and controlling the critical process parameters by timely measurements. The technology is used for granulation/agglomeration, layering and coating of a wide range of particle size. In addition; the technique can be used for the drying process as well. The three patterns of the fluid-bed processes could be characterized by the position/location of the spray nozzle i.e. top spray, bottom spray or tangential spray. These advanced pelletizing technologies are recently added to complement the actual capabilities of standard fluid bed processing for development of various dosage forms of âMultiple Unit Particulate Systemsâ (MUPS) with better therapeutic efficacy and economic benefits. The aim of this review is to review some of the general aspect of fluid bed granulation & some common techniques which are utilized in pharmaceutical industry.
