The prospects of breast carcinoma have been coupled with the increase in ubiquity of obesity over the last decade as a result of the hormonal and health complexities connected to it. More than two-thirds of female populace is being diagnosed with breast carcinoma who fall under either obese or overweight category, the association of which is found to be progressive each year. There is an affirmable increase in the risk of breast carcinoma among postmenopausal women is high when put aside with premenopausal women, with respect to its incidence in India. In most meta-analysis, systematic reviews and observational studies, obesity has been proved to be a considerable risk factor. Obesity is incident in more or less 60% of patients at diagnosis of breast carcinoma and an additional 60-75% gain in weight is observed in patients throughout the treatment. Obesity is related to higher levels of insulin and other hormones in both pre and post-menopausal women. Apart from other metabolic hormones associated with cancer and its recurrence, insulin secretion and connected proteins have long been associated with the increased risk of cancer and also its recurrence. With the leading change in food patterns and the lifestyle changes, resulted in a declining physical activity and increasing BMI in an average human population, over the past two decades. A major percentage of studies indicate that being obese can be a poor prognostic factor and is related to less favorable nodal status in addition to increased risk of contralateral illness, recurrence, co-morbidities and overall mortality.
