Mucoadhesive tablets is the preferable route of drug delivery due to the ease of administration, patience compliance, and flexibility in formulation. Every patient would always like to have an ideal drug delivery system possessing the two main properties that are a single dose or less frequent dosing for the whole duration of treatment and the dosage form must release the active drug directly at the site of action. The most frequent polymers used are those derived from HPMC 15M, HPMC 100M and HPMC 4M. The results of Swelling index, mucoadhesive strength and in vitro disintegrating time (sec) ranged from 103.12 to 93.31, 12.11 to 18.16 and 5.02 to 6.15 min respectively. The In vitro dissolution profile indicated faster and maximum drug release from the formulation F4. For the F4 formulation diffusion exponent n value is in between 0.45 to 0.89 so they are following non fickian anomalous diffusion model. Among other results, this article demonstrates that this technology depends on a detailed analysis between the polymer, the physical characteristics of the tablet, the physicochemical characteristics of the drug to be incorporated and the buccal region in which it will remain in contact.