Aim-The main aim of the study is to report the drug related problem occurred in order to prevent its recurrence Case presentation-A 23 year female patient presented with complaint of generalized swelling of body since 8 days, breathlessness since 3 days and fever since 3 days. She is Known case of seropositive inflammatory arthritis since 1 year and taking prednisolone 20 mg b.i.d. Examination-She was having tachycardia, oedema, moon shape face. Lab investigation-her serum cortisol level is elevated and anti CCP antibodies were present hence diagnosed as prednisolone induced cushingoid syndrome with seropositive inflammatory arthritis. Treatment-She was treated with Inj. Furosemide 4o mg IV b.i.d., Neb. Budesonide + Salbutamol every 6 hourly, Tab. Hydroxychloroquine 200 mg PO b.i.d., Tab. Methotrexate 15 mg PO Once a week, Tab. Calcium carbonate 500 mg PO o.d. and other symptomatic treatment. Conclusion-The prednisolone was withdrawn in tapered manner and the patient became normal and discharged.
