Herbal Formulations are highly popular worldwide because of the less side effect of the herbal formulation. Based on current research show that undeclared synthetic chemical constituents were found in the Therapeutic herbal medicines. Hence the quality of the herbal medicine are more concern by the world consumers and regulators. Intentionally or non-Intentionally some of the herbal medicine were contaminated by the microbial contamination, excessive or banned pesticide, heavy metal and chemical toxin with all possible problem. Adulteration of Herbal Medicinal Products with synthetic drug are producing major health risk and major concern to the drug regulatory agency. Some of the herbal supplements are adulterated with some unlabeled chemical constituents. Due to this take precaution against adulterated herbal medicines are necessary. In this review shown that there was many herbal medicines adulterated with chemical constituents and that was identified by different analytical techniques.