The study deals with the comparative evaluation of various extracts of Triticum aestivum (Wheat) grass and Carica papaya (Papaya) leaves by phytochemical screening followed by antioxidant and antihaemolytic activities as revealed by various parameters such as reducing power, nitric oxide (NO) scavenging activity, diphenyl picrylhydrazine (DPPH) free radical scavenging activity, superoxide dismutase assay, H2O2 and hypotonic solution induced haemolysis assay. The phytochemical screening showed high flavonoids, phenolic and alkaloids content which indicates antioxidant strength of the extract. In wheatgrass and papaya leaves n-butanol and aqueous extracts have high scavenging activities compared to ethyl acetate and petroleum ether extracts. All the four extracts (petroleum ether, ethyl acetate, n-butanol, aqueous) scavenge free radicals to a certain extent but n-butanol and aqueous extract exhibited more potential effect among all four extracts. Thus it can be concluded that there two potential extracts could be explored for further in vivo studies.