Prosopis belongs to the family Leguminosae, is a native of Americas, Africa and Asia, Prosopis species grows fast, are drought-resistant, nitrogen fixing shrubs. Extracts of Prosopis juliflora seeds and leaves have several in vitro pharmacological effects such as antibacterial, antifungal, anti-inflammatory properties. Datura metel L., is a perennial herbaceous plant, belonging to the Solanaceae family. In Ayurvedic medicine, seeds of D. metel are used to treat Skin rashes, Ulcers, Bronchitis, Jaundice and Diabetes. The present study was to evaluate the antidandruff activity of datura metel and p.juliflora and thereby developing a shampoo using the simple standard protocol. The shampoo formulated was studied for their pH using a digital pH meter and the pH of 6.82, 7.24, 6.93 and 7.42 was obtained for the extracts of leaves and seed of P. Juliflora and D.metel respectively. We found that both the extracts possessed excellent antioxidant, antibacterial and antimalassezic activity. The formulated shampoo too was found to be effect. Incorporating the extracts of Datura metal and P.juliflora into shampoo as an antidandruff agent will be useful in treating people affected with excess dandruff. Further studies are also needed to enhance the properties of the prepared shampoo.
