Abstract

Caesalpinia pulcherrima L. (Caesalpiniaceae) is an attractive plant due to its array of flowers, which appear yellow, pink, off-white, and red with yellow margins. Caesalpinia pulcherrima is also known as peacock flower. It is a common medicinal plant in India, Taiwan and South-East Asian countries. In alternative medicine, the different parts of this plant have been used as an anti-inflammatory, abortifacient, emmenagogue, bronchitis and malarial infection while fruits are employed to cure diarrhea and dysentery. In the present investigation Evaluation of Membrane Stabilizing Potential (HRBC) and antimicrobial activity of the Pods of Caesalpinia pulcherrima (Caesalpiniaceae) against Selected Microorganisms. HRBC membrane stabilization method used for evaluation of in-vitro anti-inflammatory activity and Diffusion assay (Plate method) for Antimicrobial Activity. In-vitro anti-inflammatory activity (HRBC Stabilization) of Caesalpinia pulcherrima of extracts showed good inhibitory activity in petroleum ether extract as % Inhibition of  Haemolysis 7.5 %, 22 %, 27 % and 37 % in 10, 25, 50 and 100 μg/ ml Concentration respectively. Chloroform extract and methanolic extracts of Caesalpinia pulcherrima showed moderate to good zone of inhibition against Selected Microorganisms compared with standard as Gentamicin. The HRBC membrane stabilizing property of Caesalpinia pulcherrima was found to be promising and also exhibited good antimicrobial activity.