ABSTRACT
This study was designed to evaluate the antipyretic activity of triterpenoids isolated from methanolic extract of Ziziphus mauritiana Lam root by using yeast-induced pyrexia model in rats at a dose of 200 mg/kg b.w. The results indicated Maslinic acid, 2 α–hydroxyurosilic acid and Betullinic acid (P<0.01) compounds from methanolic extract of Z. mauritiana root at a dose level of 200 mg/kg p.o., showed significant (P<0.01) reduced the elevated body temperature in experimental rat. This antipyretic activity in brewer yeast-induced pyrexia in rats throughout the observation period of 4 hours. Hence, this Plant has significant antipyretic activity when compared with the standard drug. So. It can be recommended for further studies.
