Abstract
Exploration of Tin oxide based `herbal drug formulation Vanga Parpam in terms of crystallographic structural aspects is crucial to assess the quality and performance of the drug. The present report is the second part of the research study on the drug formulation on the basis of phase purity, crystallite size and surface area, and porosity using Powder X-ray diffractograms, Raman spectra, adsorption isotherms, microscopic image during its ten step calcinations process.The results of the study confirmed the formation of nanocrystalline tin (IV) oxide without impurity in the crystal lattice of the metal oxide. The strong aggregation of the crystallites with the presence of the therapeutic elements at the surface of the crystallites indicated surface active principle of the drug and hence therapeutic activity. The above results provided an authentic assessment of the crystallite size, chemical stability of the drug sample during the preparation which could be used for the optimisation of the process parameters, standardisation of the formulation for wider acceptability and usage.
