Abstract
Hybanthus enneaspermus, a rare ethno botanical herb or a shrub distributed in tropical and subtropical regions of the world. In Ayurvedic literature, the plant is reported to cure various ailments. Spectral analysis of ethanol fraction of the extract by Gas Chromatography and Mass Spectrometry (GC-MS) results eight new compounds that have not reported earlier. In this study, an ethanol fraction from Hybanthus enneaspermus showed potent growth inhibitory activity against HEp-2 cell line with IC50 value of 19.75μg/ml. The present study indicate the potential use of traditional Indian medicinal herb as anti proliferative agents and suggests that further isolation of active anticancer compounds and evaluating its mechanism(s) are warranted.
