Abstract

The Piper betle is an important medicinal and recreational plant used widely in Indian traditional system. The leaves have also been proved to possess strong anticancer and antimicrobial properties due to the presence several bioactive components, predominantly the phenolic compounds. In our study, the silver nanobioconjugates were synthesised from betel leaves and its major component eugenol under sunlight exposure. The synthesized nanobioconjugates were characterized using UV-Visible spectroscopy, Transmission electron microscopy (TEM), Energy dispersive X-ray analysis (EDAX), X-ray diffraction (XRD), Polydispersity index, Zeta potential and Fourier transform infrared spectroscopy (FTIR). The reduction of silver ions was confirmed by UV-visible spectroscopy with peaks at 420nm. The nanobioconjugates showed the spherical in shape with 16-28nm in size and crystalline in nature. The conjugates were well dispersed with stable in nature. The FTRI data proved that the components in betel leaves act as good reductants and stabilizers for the silver nanobioconjugate synthesis. The synthesized nanobioconjugates were absolutely biocompatible in nature and are safe for human use. The results clearly suggest, that the synthesized silver nanobioconjugates from Piper betle leaves and eugenol can be used in the biomedical applications or as nanomedicine.