Abstract
The aim of the study to assess the prevalence of post-operative wound infection, prevalence of different microorganisms and its sensitivity pattern to commonly used antibiotics and its use. A total of 200 patients with gastrointestinal surgeries, such as appendicitis, ileac perforation, sigmoid volvulus, duodenal perforation and obstructed hernia were included in the study. Deep tissue culture was taken from the infected wound for microbiological examination, done by streak method, colony characters, and antibiotic sensitivity tests were done by Kirby-Bauer method. Out of the 200 patients, 22 patients had post-operative wound infections. Prevalence of wound infection was higher in Appendicitis than in other gastrointestinal surgeries. Pathogens that are prevalent in post-operative wound infection are Staphylococcus aureus (Appendicitis, Ileac Perforation, Duodenal Perforation, and Obstructed Hernia), Klebsiella (Appendicitis and Duodenal Perforation, sigmoid volvulus) Escherichia coli (Appendicitis) and Pseudomonas (Appendicitis). Isolated pathogens were tested for its sensitivity against commonly used antibiotics at the hospital. Antimicrobial Amikacin was sensitive to all isolated pathogens with very low resistance profile compare to other commonly used antimicrobials at hospital. The major identified pathogens were staphylococcus aureus, followed by Klebsiella. In spite of sterilization techniques, modern surgical equipments, prophylactic use of antibiotics, and post-operative wound infection still remains a challenge and contributes to patient’s morbidity and mortality. From our study result we concluded majority of the organisms are found to resistant leaving a much narrow space for effective treatment of the infections. If this condition persists for a longer time it may damage the chances of effective therapy. Hence, we suggested both physician and patient have to take responsible for in minimizing the antimicrobial resistance.
