Abstract
The aim of the present study was to investigate the antimicrobial effect of the sample isolated from the ethylacetate fraction of flowers of Hibiscus sabdariffa. This compound was shown to possess antimicrobial activity against bacteria and fungi, viz. Six bacterial strains were Salmonella typhi, Escherichia coli, Enterococcus faecalis, Bacillus cereus, Bacillus substilis, Lacto bacillus and two fungal strains Curvularia lunata and Candida albicans by using disc diffusion method. The anti bacterial activity of the compound isolated from ethyl acetate fraction is almost comparable with standard solvent control Chloramphenicol. The anti fungal activity is almost comparable with standard solvent control Fluconazole. From this study, it can be concluded that Hibiscus sabdariffa (flowers) reveal antimicrobial activity against various human pathogenic bacteria.
