Abstract
A simple, efficient, precise and accurate spectroscopic method has been developed and validated for quantitative estimation of Teneligliptin in bulk and pharmaceutical dosage form. Teneligliptin standard solution was scanned in the UV rang (400-200nm) in a 1cm quartz cell in a double beam UV spectrophotometer. The absorption maxima of teneligliptin were 243.6nm. The method obeys beers law in the concentration range from 10- 50μg/ml. The correlation coefficient was found to be 0.9991 and regression of the curve was found y = 0.0192x + 0.0087 with excellent recovery 99-102%. Limit of detection and limit of quantitation were found to be 0.095416 mg/ml and 0.2891mg/ml respectively. The method was validated for several parameters like accuracy, precision as per ICH guidelines. Value of % RSD and % recovery was found satisfactory, hence that the proposed method is precise, accurate and economical hence can be routine analysis.
