Abstract
A simple and sensitive UV spectroscopic method for the determination of Dabigatran Etexilate Mesylate in bulk and pharmaceutical dosage forms was described. From the solubility data 0.1 N HCl was used as solvent and shows absorption maximum at 326 nm. The Beer’s Law range is 03 – 21 μg/ml. The linear regression for method found to be 0.99982, slope 0.03158, Intercept 0.04169. When marketed formulations were analysed, the results obtained by the proposed method were in good agreement with labelled amounts. The developed method was validated statistically as per ICH guidelines. Conclusion: The developed UV-Spectroscopic method is simple, sensitive, specific and can be successfully employed in routine analysis of Dabigatran Etexilate Mesylate Pharmaceutical dosage forms in Industries as well as in routine laboratory analysis.
