Abstract
The aim of the present study was to evaluate the intensity of the anti-inflammatory and analgesic activities of Polyalthia longifolia on albino rat of either sex. The leaves of Polyalthia longifolia are an important herb used in folk eastern medicines. In this study, the hydro alcoholic extract of Polyalthia longifolia in doses of 200 mg/kg was used. Anti-inflammatory activity was evaluated by measuring the mean decrease in hind paw volume after the sub planter injection of carrageenan. Result of the study shows that hydro alcoholic extract of the dose of 200 mg/kg body weight showed significant inhibition of paw oedema after 3, 4 & 5 hrs respectively. The analgesic activity was tested against acetic acid induced writhing response using albino rats. From this study, it can be concluded that the leaves of Polyalthia longifolia possess marked analgesic activity and is equipotent to standard drug (Aspirin). Polyalthia longifolia possesses several important pharmaceutical and pharmacological properties. The current study describes that leaves of Polyalthia longifolia has significant anti-inflammatory and analgesic properties. Conclusion of the study is that this herbal medicine can be used as an alternative therapy for the treatment of minor to moderate types of inflammation and as a painkiller.
