Abstract
The purpose of this study was to assess the prescribing pattern, utilization and rationality of antibiotics utilization in the patients.A retrospective observational study of the antibiotic prescription was carried out in the medicine department of a tertiary care teaching hospital, Davangere. 175 case records of the patients were identified, assessed, evaluated and analyzed for the rational use of antibiotics for a period of 6 months.In a total of 175 prescription, 73(41.7%) prescriptions were prescribed with single antibiotic, 69 (39.4%) and 24 (13.7%) prescriptions were given 2 and 3 antibiotics respectively and 9 (5.1%) prescriptions were given with 4 antibiotics. In majority of the prescriptions Cephalosporins were prescribed, 98 (56%) were treated with combination therapy and 77 (44%) were treated with monotherapy. In this study minor DDI’s were found to be more (11). Parenteral antibiotic formulations were mostly used than oral formulations. Out of 323 prescribed antibiotics 134 were Cephalosporins, among them, Ceftriaxone were prescribed to 105 (78.3%) patients, Cefixime was prescribed to 17 (12.6%) and Cefotaxime to 12 (8.9%).It was concluded that study provides insights into the patterns of antibiotic use and rationalizing prescribing practices. The active participation of clinical pharmacists in the clinical ward rounds and documentation of pharmacist observation on prescription in patient case sheets is highly recommended for safety drug monitoring.
