Abstract
Mucoadhesive microspheres exhibit a prolonged residence time at the site of application or absorption and facilitate an intimate contact with the underlying absorption surface and thus contribute to improved and better therapeutic performance of drugs. Microspheres constitute an important part of this particulate drug delivery system because of their small size and other efficient properties. Mucoadhesive microspheres provide better drug absorption as they get adhere to the mucosal surface and release drug for prolonged time. This article reviewed about the mucoadhesive microspheres, their methods of preparation Mucoadhesive Microspheres are small spherical particles with diameter in micrometer range (1μm to 1000μm). In recent years such Mucoadhesive microspheres have been developed for oral, buccal, nasal, ocular, rectal and vaginal for either systemic or local effects. This review article aims to provide various aspects of mucoadhesion, theories of mucoadhesion and the polymers which will shows the excellent mucoadhesive properties.
