Abstract
The developments of potent anti-inflammatory, anti-oxidant drugs from the natural products are now under thought. Natural products are rich source for discovery of new drugs because of their component diversity. An herbal product from medicinal plants plays a major role to cure many diseases associated with inflammation and anti-oxidant. The traditional drug available in the market to treat inflammation produces various side-effects. There is a need for the search of newer drugs with less or no side-effects. This review is given on the anti-inflammatory activity and anti-oxidant of the most familiar medicinal plants of medicine. This matter may be helpful for the researchers, academician and preclinician to know about the potential herbs having anti-inflammatory activity and anti-oxidant activity. Adhatoda vasica. Is an indigenous herb belonging to family Acanthaceae. The flowers of Adhatoda vasica is extracted and evaluated for antioxidant activities by 2,2-Diphenyl 1-picryl hydrazyl solution (DPPH), 2,2'-azino-bis(3-ethylbenzthiazoline-6-sul- phonic acid (ABTS) assay and anti-inflammatory activities by human blood cell (HRBC) membrane stabilization method and Inhibition of albumin denaturation method. The results obtained showed that the ethyl acetate fractions of Adhatoda vasica flowers can be considered as good sources of anti-oxidants, anti-inflammatory and can be incorporated into the drug formulations. This study justifies the anti-oxidants, anti-inflammatory activity of the compound isolated from ethyl acetate fractions of Adhatoda vasica flowers. Further detailed analysis of this sample is required to identify the presence of bioactive compounds responsible for anti-oxidants, anti-inflammatory activities. Studies are highly needed for future drug development.
