Abstract
Background: Antibiotics are one of the most common drugs prescribed in the hospitals. The present survey was performed to study the style of prescription and brands prescribed of different types of antibiotic regimens in different surgeries in and assess the appropriateness of antibiotic therapy through a comparison with the standard guidelines for antibiotic prescription. Methodology: A prospective and observational study was carried to evaluate the patients undergone surgery through six months duration from January 2015 to June 2015. The total number of 500 post operative prescription of patients were enrolled in study and suitable questionnaires were prepared to collect the patient data like demographic details, type of surgery, and parameters of antibiotic therapy including selection of antibiotic, dose, route and duration of therapy were taken. Results: A total of 500 patient’s data was entered according to the patient demographic details in which 275(55%) male and 225(45%) female. The total numbers of antibiotics used were 1065 in which 55.77% of third generation Cephalosporin and 18.49% of Metronidazole were used. In the study seven different combinations of antibiotics were prescribed. The most common surgery performed was appendectomy. The number of antibiotic 183 patients receiving one antibiotic and 161 patients receiving two antibiotics and other 156 patients three or more antibiotics (antibiotic combination). Cefotaxime was the common antibiotic prescribed it was written for 300 patients as a single agent or in combination with other antibiotics. Cefotaxime with Metronidazole was the common antibiotic combination, prescribed for 148 patients. Conclusion: The role of clinical pharmacist by studying the prescribing patterns will be useful to avoid irrational use of antibiotics and Cost analysis can be useful. If implemented could reduce the economic burden on the patients by reducing the length of hospital stay.
