Abstract 

Chronic Kidney Disease (CKD) patients are most likely to die of Cardio Vascular Disease (CVD) rather than failure of kidney. The CVD diagnosis cardiac markers alterations are seen in CKD especially in hemodialysis patients. Therefore, the aim of our study is to evaluate incidence of LVH in CKD effect of CKD on cardiac biomarkers. All the cardiac markers are assessed by using ELISA except IMA, which is measured by using cobalt binding capacity method. It was observed that CK-MB and myoglobin are raised in serum the NT pro BNP and HFABP also register a rise in CKD with hemodialysis. There is also increased IMA and Cardiac troponin I (CTnI) in hemodialysis. In CKD nondialysis group, the cardiac parameters like NTpro BNP and IMA were raised compared to control. The HFABP, Myoglobin and CK-MB has not shown any significant rise when compared with control. These results suggest that elevated cardiac markers in CKD is not only due to renal status and but also influenced by other factors like LVH, skeletal muscle damage and oxidative stress.