Abstract
Addison's disease is chronic, life threatening rare endocrinal disorder which affects 1 in 100,000 people. Both sex people equally affected by this disorder. Autoimmune adrenalitis is most common cause of primary adrenal insufficiency. It's prevalence is about 140 per million. Autoimmune adrenalitis disorder, the adrenal cortex is damaged causing the loss of production of hormone such as glucocorticoid,mineralocorticoid. The fight and flight stress hormone adrenaline produced by inner medulla. The cortisol and aldosterone are the esssential steroid hormone produced by it. Function of the cortisol is to enable the body to fight inflammation, stimulates liver to produce blood sugar, mobilises nutrients, helps to balance the quantity of water in human body. While the salt & water level which have impact on Blood Pressure is regulated by aldosterone. The main objective of this review article is to create an awareness among the people concerning with the addison's disease & it's symptoms, diagnosis, treatment. Rational utilization of drug therapy with patient compliance is important.So that proper management of Addison's disease is achieved.
