Abstract
The present was carried out to know the pharmacologically active chemical constituents present in Aerva lanata (L.) Juss. Ex. Schult leaves, stem, root and flower. 2 μL of the methanolic extract of roots, flowers, stems and leaves were employed for GC-MS analysis. Mass spectra were taken at 70 eV; a scan interval of 0.5 s and fragments from 45 to 450 Da. The MS detection was completed in 36 minutes. The compound biological activity prediction is based on Dr. Dukeâs Phytochemical and Ethnobotanical Databases by Dr. Jim Duke of the Agricultural Research Service/USDA and PASS. The A. lanata methanolic root, flower, stem and leaves extracts revealed the presence of 23, 25, 23 and 23 different compounds respectively. The A. lanata methanolic root, flower, stem and leaves extracts. The Dukes database and PASS prediction results showed that the major components displayed different biological activities such as antineurotoxic, anticarcinogenic, antialcoholic, antiviral, antiinflammatory, antiprotozoal, antiparasitic, antimutagenic, antineoplastic, antianemic, antiamyloidogenic, antimetastatic, antimycobacterial, antituberculosic, anticataract, cytoprotectant, fibrinolytic, immunomodulator, antileprosy, antianorexic, antirickettsial, CNS active muscle relaxant and psychostimulant. The present study results suggest that methanolic extract of Aerva lanata is a potent therapeutic agent. Further work is needed to isolate and identify these bioactive compounds.
