Abstract
The purpose of the study was to prepare an open drug formulary for the medicine department of tertiary care teaching hospital and publish it in a convenient size and format. The study was conducted in a tertiary care teaching hospital for a period of six months. The final master list of drugs was prepared in accordance with the opinion of the physicians. Then monograph for the drugs were prepared by referring Micromedex, NFI, and other authentic resources. After the completion of the monographs, they were given to five physicians and five lecturers for validation. The fixed dose combinations, vitamins and minerals were enlisted. Finally the formulary was published in a more convenient size and format for a quick reference. There were about 533 generic drugs are used in the medicine department of SSIMS & RC. The drug list was prepared with 533 drugs. From those, drugs were categorized according to pharmacotherapeutic classification and finally classified according to the organ systems. Monographs of 350 drugs were completed and given for validation. After the validation, appropriate changes were made and formulary was prepared. Micromedex was the main resource used for monograph preparation. Out of 350 monographs, the half-life of 34 drugs, volume of distribution of 139 drugs and clearance of 252 drugs were not found and not documented. Drug interactions for 23 drugs were not found and documented. The more number of drugs are under pregnancy risk category C compared to category A, B, D, X and N.
