Abstract
For antibacterial activity the methanolic extracts of 12 plants leaves were extracted. The antibacterial testing in vitro was done following disc diffusion method against Bacillus subtilis, Erwinia herbicola, Escherichia coli, Salmonella typhi, Pseudomonas putida Staphylococcus aureus Klebsiella pnemoniae ,Vibrio cholera.Amongst the leaf methanolic extracts tested, the extracts of Aegle marmelos (L.) Corre, Anethum graveolens L and Eupatorium capillifolium (Lam.) Small showed significant antibacterial activity against the bacterial pathogen. Putranjiva roxburghii Wall showed highest antibacterial activity followed by Artabotrys hexapetalus (L.f.) Bhandari. The 2, 2-diphenyl-1-picrylhydrazyl (DPPH) radical scavenging assay was used to determine the antioxidant activity of potent extract. Putranjiva roxburghii Wall showed the appreciable antioxidant activity. This showed highest antioxidant activity at 40 mg/ml concentration with a percent inhibition of 65.54 and IC50 value 7.29 mg/ml. The reducing power of the extracts was found to increase with increasing concentration of the extract .The results provide evidence that the methanolic leaf extract extract of Putranjiva roxburghii can be further recommended in the treatment of the infections caused by the bacterial pathogens .The result indicates that Putranjiva roxburghii is a potential source of antibacterial and natural antioxidants.
