Abstract
The anticancer activity of the extract of Dolichandrone atrovirens (DA) has been evaluated against Dalton’s ascitic Lymphoma (DAL) in Swiss albino mice. It has a significant enhancement of mean survival time of treated groups tumor bearing mice was found with respect to DAL control group. Drug treatment was found to be an increase non-viable cell counts. After the treatment of extracts with DAL bearing mice shows that the tumor cell growth was found to be inhibited. After 14 days of inoculation, extracts is able to reverse the changes in the hematological parameters, liver function test and PCV consequent to tumor inoculation that near to the normal control group. The DA were decreased the ascitic fluid volume, viable cell count, and increased the percentage of life span of animals. It may be concluded that DA by decreasing the nutritional fluid volume and arresting the tumor growth, this could be the reason for the increase life span of DAL-bearing mice.
