Abstract

Present study is aim to formulate and evaluate the Valsartan-Hydrochlorothiazide (160/25mg) film coated tablets. The oral route is most important and preferable for the delivery of drugs to the systemic circulation due to the ease of administration, patient compliance and flexibility etc. These tablets produce reduction in the multiple dosing and more effective in management of the hypertension. The combination tablets of two hypertensive drugs are formulated accordingly that one drug released early and second drug give sustained release. The film coating was used form the sustainability of drug release. All the official and non-officialparameters were evaluated for the coated tablets. The tablet passes all the evaluation parameters. On the stability stress of three months the prepared formulations were fond stable. The prepared tablet found compatible and convienent to the patient in the management of hypertension.