Abstract
Hypertension is a common condition with high mortality from associated diseases. Epidemiological evidence suggests that a deficiency of vitamin D may be a risk factor for hypertension. The objective was to conduct systematic review and analyze the effect of vitamin D supplementation as a supportive antihypertensive therapy. Effect of vitamin D supplementation on hypertensive patients, a prospective observational study was performed on30 out-patients, who were suffering from hypertension and fitted the study criteria in general medicine department of Princess Esra hospital. All the data required for the study was collected, reviewed and recorded. Subjects were prescribed with anti hypertensive drugs alone for 45 days and then the prescription was added with vitamin D supplements for next 45 days. Changes in blood pressure readings were compared. Using the paired t- test the results were significant. In patients who were given vitamin D the average systolic blood pressure with anti hypertensive was 140 ±9.2mmHg, the average systolic blood pressure with both anti hypertensive drugs and vitamin D was found to be 136±5.6mmHg. The diastolic blood pressure doesn’t seem to have much fluctuation on vitamin D intake. From observations it can be concluded that combining vitamin D along with anti hypertensive therapy had moderate blood pressure lowering effect.
