Abstract

Patients admitted to the Indoor patient department receive multiple medications from a variety of pharmacological classes due to various life threatening illnesses. This study was conducted to assess the patterns of prescribing antimicrobial agents to achieve rational therapeutic practices in order to Prevent Drug- Drug Interactions. The aim of this study is to evaluate the pattern of antibiotic usage amongst the patients admitted in Medicine IPD (Indoor Patient Department) in a tertiary care teaching hospital in Uttar Pradesh. It is an Observational study was carried out at UP RIMS & R, Uttar Pradesh from 20th November 2014 to 15th January 2015. The relevant data of drug was collected from the prescription of each patient in the indoor ward. The demographic data, disease pattern and the use of different classes of antimicrobial agents as well as other drugs were analyzed. Data were analyzed using Microsoft Office Excel 2007 and values were presented descriptively in percentiles. Altogether 231 patients, 146 (63%) males and 85 (37%) females were enrolled. Highest rate of drug prescription was observed for patients aged between 25 to 40 years. Highest rate of antimicrobial prescription was observed for the patients of Diabetes Mellitus which consist of 22.5% patients followed by other complications. Highest frequency of drug prescription was observed for Cephalosporin which consist of 268 (48%) followed by other drugs. Overall 36% patients were treated with a monotherapy antimicrobial. This study showed that average drug prescribed per prescription was 4.05. In conclusion different types of clinical disorders were noticed. Overall poly‐pharmacy among antimicrobial agents was noticed. Hence, we have attempted to show the current pattern of antimicrobials being used and to promote rational prescribing.