Abstract
In DNA vaccines the foreign DNA is used to express an encoded protein & fuel the body’s immune system. It represents a new approach to immunization which is potentially less exclusive than the older vaccines. After inoculation into the host, DNA enters the cells, where the antigen is expressed, processed & then predictable by immune system as in a natural infection. Certain methods like gene gun & electroporation are used to deliver DNA vaccines.DNA vaccines undergo through clinical trials to find the way to treat autoimmune diseases, hepatitis, mycobacterium diseases, allergy & malaria. This review focuses on mechanism by which DNA vaccination induce immune response, delivering method & applications of DNA vaccinations.
