Abstract
Cancer is an important area of interest in the life sciences because it has been a major killer disease throughout human history. Pyrrolopyrimidines are well known to play a critical role in health care and pharmaceutical drug design. Currently a number of Pyrrolopyrimidines are available commercially as anticancer drugs and great efforts have been put to the identification of novel anticancer targets for novel anticancer drug discovery. The focus of this review is to provide a comprehensive and up-to-date account on the most recent development in the medicinal chemistry of pyrrolo[2,3-d]pyrimidine derivatives with significant anticancer activity starting from the last exhaustive publication in this field.
