Abstract
The benzimidazole nucleus does not appear to occur very widespread in nature. Commonly they are synthesized from o-phenylenediamines hence they are named as derivatives of o-phenylenediamines. Benzimidazoles are regarded as a promising class of bioactive heterocyclic compounds that exhibit a range of biological activities. Specifically, this nucleus is a constituent of vitamin-B12. This ring system is present in numerous antiprotozoal antihelmintics, anti-HIV, anticonvulsant, antiinflammatory, antihepatic, antineoplastic, and antiulcer, activities. A large number of patents describe benzimidazole derivatives of use in the textile industry as wetting, emulsifying, foaming, or softening agents or as dispersants for use in dyeing.
