Abstract
During antidandruff activity of various aromatic plant oils viz., Syzygium aromaticum (PCL 000201337), Foeniculum vulgare (PCL 00201338, Trachyspermum ammi (PCL 00201339), the essential oil of Syzygium aromaticum was found to be the most potent antidandruff agent, inhibiting the mycelial growth of test pathogens viz., Malassezia furfur (MTCC 1374) and Malassezia pachydermitis (MTCC 1369) completely. The MIC of the oil was found 0.312 l/ml concentration inhibited the tested pathogens while at 0.625 l/ml showed fungicidal concentration. Oil also found to be thermostable up to 1000C and did not expired upto 48 month of storage. The gas liquid chromatographic (GLC) analysis of the oil indicated it to be a mixture of 1 major (eugenol) and 25 minor components. The oil was found many time more effective in comparison to synthetics drugs, itraconazole and fluconazole. Thus, the essential can be recommended for safe, thermostable and long duration effects without any adverse effect and could be used as potential natural remedy after undergoing successful in vivo trials.
