Abstract
A simple, accurate, sensitive and reproducible spectrofluorimetric method has been developed for the analysis of Silodosin in pure and pharmaceutical dosage form. Silodosin shows strong native fluorescence in methanol having excitation wavelength at 272 nm and emission wavelength at 450 nm. The calibration graph was linear in the range from 0.01 to 1μg/ml. The proposed method was statistically validated and successfully applied for analysis of capsule dosage form. The limit of detection and limit of quantification were found to be 0.003μg/ml and 0.0091μg/ml respectively. The percentage recovery was found to be in the range of 98.53% ± 0.53 to 99.27% ± 0.49.
