Abstract

Application of modern scientific tools and techniques is important for the quality evaluation and standardization of polyherbal formulations. Herbal formulations that are being prepared on traditional methods lack quality and batch-to-batch consistency. The present study aimed to develop an ayurvedic polyherbal extract into a capsule dosage form, evaluating its physio-chemical, phytochemical, formulation parameters and setting up its quality control standards. Hard gelatin capsules for oral administration were prepared by lyophilizing the traditional liquid dosage form of the standardized extract. The formulation was then characterized as per pharmacopoeial standards. The variation of weight among the capsules was least, which showed a good ratio of excipients in the formulation with dissolution of 92%.The current work revealed that encapsulation of the lyophilized extract resulted in the concealing of bitter taste. It can be concluded that these parameters can be conveniently used to check the quality control of various herbal formulations thereby paving a way for their pharmacological activities.