Abstract

The classical Siddha poly-mineral drug Panchalavana Thiraavagam has unique properties being a specialized liquid form of medicine indicated for PCOS as per traditional Siddha literature Kannusamiyam Ennum Vaidhiya Saegaram. The aim of this present study was to standardize the purity, quality and safety of Panchalavana Thiraavagam. The physico-chemical characterization of the drug was revealed by qualitative biochemical analysis and modern instrumental techniques such as Fourier Transformation Infrared Spectroscopy (FT-IR), Scanning Electron Microscopy (SEM), Energy Dispersive X-ray analysis (EDAX). Physico-chemical parameters revealed that the drug is clear, colourless fluid with no characteristic odour and weak acidic (pH 6.2) in nature. The qualitative biochemical analysis revealed that the presence of Sulphate, Chloride, Phosphate, Calcium, Sodium and Potassium. The FT-IR study revealed the presence of functional groups like aliphatic bromo compounds, nitro group, ketones, carbonyl group, phenols and alcohols in Panchalavana Thiraavagam.  The SEM analysis showed that the size of the particles to be 80.0 nm, 94.1nm, 102nm, 113nm, 330 nm in the sample. So it was concluded that the Panchalavana Thiraavagam contains essential elements required to the body. Also the drug possesses no toxic effects because of absence of toxic metals. Thus the present study paves the way for toxicological and pharmacological activities.