Abstract
Within the medicine system medicinal plants and their derivatives play a cruciall role to conserve our health. The present study was aimed to identify the potential bioactive compounds from parts of Passiflora foetida L. through GC-MS analysis. The plant was also analysed for α-amylase and α-glucosidase inhibitory activity. The results of phytochemical screening revealed the presence of alkaloids, flavanoids, tannins, phenols, steroids, cardioglycosides, saponins and terpenoids werepresent in almost all the parts of P. foetida L. In the GC-MS analysis, 27 bioactive compounds were identified in the seed ethanolic extract of Passiflora foetida L. Maximum α-amylase inhibitory activity was recorded in 100 µg/ml of aqueous and ethanolic extract of root with an inhibition of 80.3% and 83.3% respectively. In α-glucosidase inhibitory activity, the aqueous extract of seed of 72.3%) P. foetida showed a maximum inhibition of 72.3% followed by ethanolic extract of root with an inhibition of 65.7%.This study provide an evidence that the bioactive comp[ounds present in P. foetida exert α-amylase and α-glucosidase inhibitory activity and also authenticate its use in the management of diabetes.
