Abstract

Mononuclear phagocytic system causes the elimination of platelets with the help of antibodies and as result immune mediated thrombocytopenia (IMT), which there is activation of auto- or allo-antiglobulins against thrombocytes leads to its premature destruction by macrophagic engulfment in dogs. Immune system due to presence of other disorder my cause the destruction of platelets so by confirming the absence of secondary disorder is an evidence that immune system is responsible for causing destruction of platelets and this type of thrombocytopenia is primary immune mediated thrombocytopenia and it can be treated by suppressing immune system with the help of immune suppressive therapy while the thrombocytopenia caused by presence of any other disorder is secondary immune mediated thrombocytopenia which can be treated by removing that disorder which is responsible or due to which this type of immune mediated thrombocytopenia has been occurred or we can also give immune suppressive drug.If dogs suffering from immune mediated thrombocytopenia do not show any response to the therapy then additional immunotherapy can be given and in some cases the examination is repeated again in order to find out any other cause involved which may be left to be identified.